Ex parte DOW - Page 2




              Appeal No. 1997-1856                                                                                      
              Application 08/142,284                                                                                    

                     In rejecting the appealed claims on non-prior art grounds, the examiner relies on the              
              following references:                                                                                     
              Kruse et al. (Kruse), “Synthesis and Evaluation of Multisubstrate Inhibitors of an Oncogene-              
              Encoded Tyrosine-Specific Protein Kinase,” J. Med. Chem., Vol. 31, No. 9,  pp. 1768-772                   
              (1988)                                                                                                    
              Levitzki, “Tyrphostins: tyrosine Kinase blockers as novel antiproliferative agents                        
              and dissectors of signal transduction,” The FASEB Journal, Vol. 6, pp. 3275-282                           
              (Nov. 1992)                                                                                               
                     The issues presented for review are: (1) whether the examiner erred in rejecting                   
              claims 1 through 4 under 35 U.S.C. § 112, first paragraph, as based on a non-enabling                     
              disclosure; and (2) whether the examiner erred in rejecting claims 1 through 4 under                      
              35 U.S.C. § 112, second paragraph, as indefinite.                                                         
                     On consideration of the record, we reverse the examiner's rejection under                          
              35 U.S.C. § 112, first paragraph.  We remand this application to the examiner for                         
              clarification and further proceedings respecting the rejection under 35 U.S.C. § 112,                     
              second paragraph.                                                                                         


                                       35 U.S.C. § 112, FIRST PARAGRAPH                                                 
                     The examiner acknowledges that appellant's specification enables any person                        
              skilled in the art to make the instantly claimed compounds (Examiner's Answer, page 4,                    
              lines 4 and 5).  The examiner argues, however, that the specification does not enable any                 
              person skilled in the art to use the claimed compounds (Examiner's Answer, page 4, lines                  

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