Ex Parte Brown et al - Page 2

                Appeal 2007-2955                                                                              
                Application 10/190,425                                                                        

                                              BACKGROUND                                                      
                      “Living cells utilize unique and elaborate sets of surface molecules,                   
                which provide for signaling pathways, interactions with other cells,                          
                structural variation, function, and the like” (Spec. ¶ 2).  “The behavior and                 
                fate of a cell is strongly dependent both on [its] internal state, and on                     
                complex cell-cell and cell-ECM [extra cellular membrane] interactions                         
                mediated by such cell surface molecules” (id.).                                               
                      The present invention is directed to methods “in which cells are                        
                profiled with respect to their expression of cell surface molecules, and                      
                ability to respond to external stimulus in the microenvironment” (id. at ¶ 8).                
                                       STATEMENT OF THE CASE                                                  
                      Claims 1-4, 6, 10, 31, and 33 stand rejected under 35 U.S.C. § 103(a)                   
                as unpatentable over Belov3 or Chang,4 in view of Taylor5 and Wagner.6                        
                      Appellants indicate that “Claim 31 is separately considered, as it is                   
                drawn to methods wherein at least two cell types interact[,] [and] Claim 33                   
                is separately considered, as it is drawn to hydrogel coated slides” (Appeal                   
                Br. 9-10).  However, Appellants do not present separate arguments for the                     
                patentability of these claims.  “A statement which merely points out what a                   
                claim recites will not be considered an argument for separate patentability of                
                a claim.”  37 C.F.R. § 41.37(c)(1)(vii).  Therefore, we will focus on claim 1                 

                                                                                                             
                3  Belov et al., Immunophenotyping of Leukemias Using a Cluster of                            
                Differentiation Antibody Microarray, 61 Cancer Research 4483-4489 (June                       
                2001).                                                                                        
                4  U.S. Patent 4,591,570 to Chang, issued May 27, 1986.                                       
                5  U.S. Patent 6,103,479 to Taylor, issued August 15, 2000.                                   
                6  U.S. Patent 6,329,209 B1 to Wagner et al., issued December 11, 2001.                       

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