Ex parte CARLE et al. - Page 8




          Appeal No. 93-2757                                                          
          Application 07/908,856                                                      


               We shall not pass on the question whether the invention                
          defined in claim 14 would have been prima facie obvious over                
          GB 2 170 404 A.  Rather, for the purposes of this appeal, we                
          shall assume arguendo that GB 2 170 404 A establishes a case                
          of prima facie obviousness of this claim.  The Carle                        
          Declaration, however, rebuts any such prima facie case.                     
               In the Carle Declaration, executed May 20, 1992, the                   
          declarant conducted side-by-side tests comparing the aqueous                
          distillation of fresh and dried camomile flowers.  Both                     
          distillations were carried out “exactly as in Example 7 of                  
          British patent 2 170 404.”  As reported in the declaration,                 
          the aqueous distillation of fresh flowers provided a                        
          significantly enhanced yield of (-)-"-bisabolol, chamazulene,               
          cis-spiroether and trans-spiroether.                                        
               The examiner does not critique the Carle Declaration in                
          any manner whatsoever, e.g., by arguing that the tests therein              
          are not truly comparative or that the results achieved are                  
          merely expected or that the enhanced yields of (-)-"-                       
          bisabolol, chamazulene, cis-spiroether and trans-spiroether                 
          are insignificant.  On the contrary, with respect to the                    
          declaration evidence, the examiner is silent.  This                         


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