Appeal No. 94-2477
Application 07/893,554
Noyes describes Table 3 at page 644 as follows:
The numbers of patients reporting various side effects are shown in Table 3. In addition
to sedation, dizziness, blurred vision, ataxia, and slurred speech appeared to be dose-
limiting effects. Negrete has defined severe marijuana intoxication as a mild delirium
consisting of impaired sensorium, disorientation, slurred speech, and ataxia. According to
this author’s classification, approximately a third of patients became severely intoxicated
following 20 mg of THC. Three patients were similarly effected by the 10 mg dose.
Increased appetite, which was frequently reported after 10 mg of THC, was less
commonly described following 20 mg. This effect may have been obscured by other
manifestations of the larger dose. [Footnote omitted.]
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