Ex parte PEHRSON ET. AL. - Page 2




          Appeal No 94-2912                                                            
          Application 07/752,831                                                       
               This is an appeal from an examiner’s rejection of Claims                
          1, 23, 31-33 and 39-41, all claims pending in this                           
          application. Claims 1, 23, 31-33 and 39-41 stand rejected                    
          under 35 U.S.C.                                                              
          § 103 as being unpatentable in view of the combined teachings                
          of Packman, U.S. Patent 4,945,084, issued July 31, 1990, from                
          an application filed July 8, 1987; Lazaridis et al.                          
          (Lazaridis), U.S. Patent 4,990,610, issued February 5, 1991,                 
          from an application filed December 16, 1988; Bristol et al.                  
          (Bristol), U.S. Patent 4,361,567, issued November 30, 1982;                  
          Mitsuhashi                                                                   
          et al. (Mitsuhashi), U.S. Patent 4,812,444, issued March 14,                 
          1989; and The Merck Index, Ninth Edition, Merck & Co., Inc.,                 
          Compound Nos. 1832, 4675, 7360, and 8283, pages 23, 630, 985,                
          1103 and 1104, (1976).                                                       
               Claims 1 and 23 are representative of the subject matter                
          claimed and read:                                                            
               1.   A method of treating a patient suffering from an                   
                         aphthous ulcer, the method comprising                         
          administering                                                                
                    to said patient a topical preparation containing                   
                    sucralfate as an essential ingredient, wherein:                    
                    (a) the sucralfate is admixed with an aqueous                      
                         carboxypolymethylene medium containing                        
                         polysorbate 80 and simethicone, said medium                   
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