Ex parte KOLB et al. - Page 7




          Appeal No. 96-0401                                         Page 7           
          Application No. 08/127,304                                                  


               [t]he Manns patents both discloses a multiwell test plate              
               assembly comprising a holding tray (24), a filter medium               
               (22) received in the holding tray, a collimator (20)                   
               having wells (28), and a carrier plate (26) for                        
               supporting the holding tray.  The Manns patents fail to                
               teach 1) the collimator being removably disposed in the                
               holding tray and 2) the holding tray being a solid plate               
               without holes.  Even though all the structural parts of                
               the Manns' assembly are thermally bonded whereby all                   
               parts are integral, it would have been obvious to one of               
               ordinary skill in the art to make the parts separable . .              
               .  Furthermore, it would have been obvious to one of                   
               ordinary skill in the art to make the holding tray from a              
               solid plate without holes for the extended storage and                 
               analysis of biological samples.                                        


               The appellants argue (brief, pp. 8-14) that the subject                
          matter of claim 1 would not have been suggested by the                      
          teachings of Manns '442 or Manns '215.  We agree for the                    
          reasons set forth below.                                                    


               We agree with the examiner (answer, p. 6) that the                     
          collimator (20) is initially separable from the holding tray                
          (24).  Accordingly, prior to the thermal bonding of the                     
          collimator (20) to the holding tray (24) it would be                        
          appropriate to characterize the collimator (20) as being                    
          removably disposed within the holding tray (24).  However, we               
          see no evidence, as shown by some objective teaching in the                 







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