Ex parte BASHKIN et al. - Page 4




          Appeal No. 1995-1304                                                         
          Application No. 07/947,071                                                   


                                      DISCUSSION                                       
               The examiner argues that appellants' specification is                   
          insufficient to support the scope of claims 1, 3 through 8, 10               
          through 16, 20 through 23, and 25 through 30.  According to                  
          the examiner, the specification does not provide adequate                    
          guidance enabling any person skilled in the art to make                      
          compounds which hydrolytically cleave RNA except for the                     
          compounds enumerated in allowed claims 31 through 33.  We                    
          disagree.                                                                    
               As stated in In re Armbruster, 512 F.2d 676, 677-78,                    
          185 USPQ 152, 153 (CCPA 1975) quoting from In re Marzocchi,                  
          439 F.2d 220, 223-24, 169 USPQ 367, 369-70 (CCPA 1971):                      
               As a matter of Patent Office practice, then, a                          
               specification disclosure which contains a teaching                      
               of the manner and process of making and using the                       
               invention in terms which correspond in scope to                         
               those used in describing and defining the subject                       
               matter sought to be patented must be taken as in                        
               compliance with the enabling requirement of the                         
               first paragraph of § 112 unless there is reason to                      
               doubt the objective truth of the statements                             
               contained therein which must be relied on for                           
               enabling support. . . .                                                 
               . . . [I]t is incumbent upon the Patent Office,                         
               whenever a rejection on this basis is made, to                          
               explain why it doubts the truth or accuracy of any                      
               statement in a supporting disclosure and to back up                     
               assertions of its own with acceptable evidence or                       

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