Ex parte PAREKH et al. - Page 3




           Appeal No. 95-1881                                                                     
           Application 08/032,166                                                                 
           reasons stated in appellants’ Appeal Brief.   In our view, the2                                    
           examiner has not satisfied the PTO’s initial burden to                                 
           adequately explain: (1) why persons having ordinary skill in                           
           the art would not have recognized from the specification,                              
           especially Figure 3, that applicants invented the claimed                              
           method for releasing an                                                                
           O-glycan by reacting a glycoconjugate with a hydrazine reagent                         
                         O              O                                                        
           at “about 55 C to about 75 C at 8 hours”; (2) why the                                  
           specification would not have enabled persons skilled in the                            
           art to make and use the method claimed wherein the hydrazine                           
           reagent is “a hydrazine-containing compound” without undue                             
           experimentation; and (3) why the method claimed would have                             
           been obvious to a person having ordinary skill in the art in                           
           view of Montreuil’s teaching.                                                          
                                            REVERSED                                              


           Teddy S. Gron                   )                                                      
                 Administrative Patent Judge     )                                                
                       )                                                                          

                2     At oral argument, counsel for appellants noted                             
           Parekh et al., U.S. Patent 5,539,090, patented July 23, 1996,                          
           from Application (continued...) 08/195,761, filed March 12,                            
           1993, as a continuation of Application 07/719,287, filed June                          
           21, 1991, abandoned.                                                                   

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