Ex parte PASTAN et al. - Page 3




               Appeal No. 95-2052                                                                                                 
               Application 07/620,939                                                                                             


                      263, No. 19, pp. 9470-9475.  (Jul. 1988).                                                                   





                      Previously entered rejections of the claims under 35 U.S.C. § 112, first and second                         

               paragraphs, have been withdrawn.  See the Examiner's Answer, pages 2 and 5.                                        

                      The issue remaining for review is whether the examiner erred in rejecting claims 8, 10, 14 and              

               15 under 35 U.S.C. § 103 as unpatentable over the combined disclosures of Batra 1989, Batra 1990,                  

               Pastan, Youle, and Kondo.                                                                                          

                      On consideration of the record, we shall reverse the examiner's prior art rejection.                        


                                                         DISCUSSION                                                               
                                                                    2                   3                                        
                      As a preliminary matter, we note the Frankel  and Williams et al.  references cited in the                  

               Appeal Brief,  pages 4 and 5.  In the Examiner's Answer, page 6, the examiner states that these                    

               references are relied on to "buttress" the rejection under 35 U.S.C. § 103.  See also the Supplemental             

               Examiner's Answer (paper no. 31), sentence bridging pages 2 and 3, where the examiner again refers                 

               to Frankel and Williams et al.  The problem here is that Frankel and Williams et al. are not included in           



                      2 Frankel, "Immunotoxins", published 1988 by Kluwer Academic Publishers  (Boston), pages  123-              
               140 .                                                                                                              
                      3Williams et al, J. Biol. Chem., vol. 265, pages 11885-11889, (1990).                                       
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