Ex parte TAYLOR et al. - Page 5




                     Appeal No. 95-2743                                                                                                                                                
                     Application 08/023,016                                                                                                                                            

                     absence, is any response by the examiner to the teachings of these references.  Absent                                                                            
                     evidence to the contrary, we must presume that the appellants’ references reflect the                                                                             
                     thinking of those skilled in the art with respect to useful treatments of neurodegenerative                                                                       
                     disorders; i.e., that these references demonstrate that one skilled in the art would not                                                                          
                     question the specification’s statement of utility.                                                                                                                
                                Accordingly, the rejection is reversed.                                                                                                                
                                                                                        II.                                                                                           
                                Turning to the rejection under the first paragraph of § 112, we find the examiner                                                                      
                     argues that:                                                                                                                                                      
                                                     The following claims fail to identify a host with the treating [sic]:                                                             
                                           4-19.  Further, “a compound having anticonvulsant properties...etc.” is                                                                     
                                           broader than specific supporting embodiments.                                                                                               
                                                     Those claims are broader than warranted.  As discussed                                                                            
                                           supra, there is no effective dementia treatment, and Applicants failed                                                                      
                                           to establish that Applicants’ in-vitro assay reasonably predicts                                                                            
                                           successful dementia therapy.  Therefore, it would require undue                                                                             
                                           experimentation by one skilled in the art to employ the method                                                                              
                                           because she would have to determine whether it worked or not                                                                                
                                           without guidance from Applicants [Answer, pp. 3-4].                                                                                         
                                We find these arguments unpersuasive.                                                                                                                  
                                First, it is not clear what the examiner intends by her statement that claims 4-19 fail                                                                
                     to identify a host.  These claims are dependent on claim 2 which identifies the host as a                                                                         
                     “mammal.”  The examiner has not raised any objection with respect to the                                                                                          



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