Ex parte KAPLAN et al. - Page 8




              Appeal No. 1995-3047                                                                                         
              Application No. 07/805,729                                                                                   


                     The rejection of claims 22 through 24 under 35 U.S.C. § 112, first and second                         
              paragraphs, is reversed.                                                                                     
                     Each § 103 rejection presents the same question, namely, whether the particular                       
              salt forms of d4T, ddI and F-ddI recited in the appealed claims would have been obvious in                   
              view of the parent compounds d4T, ddI and F-ddI.  We answer that question in the                             
              negative.                                                                                                    
                     As can be seen from a review of appellants' claims, each salt contains 0.5 to 2.0                     
              moles of water and variable X (appellants' terminology) is an alkali or alkaline earth metal                 
              ion, an ammonium ion, or a quaternary amino ion.  According to the examiner, the cited                       
              prior art discloses parent compounds d4T, ddI and F-ddI, but does not disclose salt forms                    
              of those parent compounds.  Nor does the examiner rely on "secondary" art to make up                         
              this difference.  Rather, the examiner relies on Ex parte Matheson, 92 USPQ 255 (P. O.                       
              Bd. of Appeals 1951) for its discussion of "the question of patentability of salts of known                  
              compounds".  See the Examiner's Answer, page 9, lines 5 through 13; page 10, lines 16                        
              through 24; and page 11, lines 17 through 25.                                                                
                     The examiner's reliance on Ex parte Matheson is misplaced.  In Matheson, the                          
              examiner rejected claims drawn to the copper, zinc and iron salts of tetra-isobutyl phenol                   
              sulfonic acid "as not patentably distinguishing" over the sodium salt of that same acid                      
              disclosed in the prior art.  The Board of Appeals reversed the examiner's decision, holding                  


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