Ex parte KHAN et al. - Page 8




          Appeal No. 1997-0926                                                        
          Application No. 08/552,045                                                  


               that an effective amount of vitamin E will be in                       
               contact with the blood during storage.                                 
               It is believed that any method of incorporating the                    
               vitamin E into the blood bag system so as to increase the              
               blood stability is suitable for the present invention.                 
               For example, the vitamin E can be present in the                       
               blood-containing compartment or can be stored in a second              
               sealed compartment attached to the main body of the bag                
               or the tubing and then added to the blood after blood                  
               collection. (Col. 7, lines 3-18).                                      
               The examiner describes Valentine as teaching "the coating              
          of the inside of a blood bag with lubricous vitamin E"                      
          (answer, page 4) and concludes that "[i]t would have been                   
          obvious to one of ordinary skill in the art to add the vitamin              
          E to the silicone resin of the inner layer of the blood bag of              
          Yoshida to increase blood component stability" (id. at 4 and                
          5).                                                                         
               In our opinion, the examiner’s stated position is based                
          on impermissible hindsight gleaned from appellants' own                     
          disclosure and not from any fair teaching or suggestion found               
          in the applied Yoshida and Valentine patents themselves.                    
          Contrary to the                                                             
          examiner's assertion, Valentine does not disclose that vitamin              
          E                                                                           


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