Ex parte DENYER et al. - Page 5




          Appeal No. 99-0230                                                          
          Application No. 08/396,277                                                  

               means for generating turbulence in said airstream                      
               due to inhalation by the patient;                                      
               a microphone selectively responsive to said                            
               turbulence due to inhalation to generate a control                     
               signal; and                                                            
               control means coupled to said nebulizer means and                      
               responsive to said control signal to cause said                        
               nebulizer means to generate said aerosol . . . .                       
          Independent method claim 11 includes these same limitations.                
               All of the claims stand rejected as being unpatentable                 
          over the combined teachings of Edgar, Henry, the textbook, and              
          Snook.  We do not agree, and we therefore will not sustain the              
          Section 103 rejection.  Our reasoning follows.                              
               Edgar discloses a drug delivery arrangement in which                   
          inhalation by the patient is sensed by a spring-mounted device              
          mounted in the airstream delivery duct means, which senses                  
          that an appropriate airstream is being pulled through the duct              
          by being deflected from its at rest position, whereupon it                  
          provides a signal to the nebulizer to inject the drug into the              
          airstream.  Edgar fails to disclose the required turbulence                 
          generating means and the microphone that reacts to the noise                
          caused thereby, which in the appellants’ system is indicative               
          of the level of flow of the airstream through the duct during               
          the patient’s inhalation.                                                   
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