MORRISON et al. V. MANNHEIMER et al. - Page 17




          Interference No. 103,197                                                      


               requirements.  Basically, the instrument consists of a 5-                
               F-diam[eter] bundle of rigid, fused fibers in a standard                 
               15-19 gage hypodermic needle.  [Our emphasis.]                           
          Kapany goes on to explain (p. 186, 2d full para.) that                        
          Figure 7.16 shows several techniques for illuminating the                     
          tissue under examination, including a transillumination                       
          technique (see Fig. 16(b)) that employs two axially aligned                   
          hypodermic probes, one for supplying illuminating radiation to                
          the tissue and the other to receive the radiation that is                     
          transmitted through the tissue region.  Kapany notes that                     
          because in most subcutaneous tissues gross changes in color or                
          composition are not observable, such tissues are ordinarily                   
          observed under a polarizing microscope, phase contrast                        
          microscope, or interference microscope (p. 188, lines 15-18).                 
          It is also possible to stain subcutaneous tissue using a very                 
          narrow auxiliary channel in the hypodermic probe (p. 188,                     
          lines 20-22) or to use the probe in the fluorescence mode by                  
          ultraviolet radiation (p. 188, lines 26-30).                                  
               Section 2 does not discuss using hypodermic probes for                   
          spectrophotometry in general or for oximetry in particular.                   
          Instead, those applications are described in Section 3, which                 
          spans pages 188-97, and begins as follows:                                    

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