BARBACID et al. V. BROWN et al. - Page 22




              Interference No. 103,586                                                                                   

              and FPP as the farnesyl source.  He does not corroborate Reiss’s testimony as to brain                     
              tissue as the source of the enzyme.  And he does not corroborate the use of a test                         
              substance in the screening assay as required by the count.  Lastly, Casey’s testimony that                 
              a coinventor showed him the results of a study are not sufficiently explanatory to establish               
              that the inventors were in possession of the subject matter of the count.  In each instance,               
              the testimony offered by Brown relates to finding the enzyme which serves to transfer the                  
              farnesyl to the ras substrate but does not relate to the use of test substance in an assay                 
              containing FT enzyme, a farnesyl acceptor substance or a protein or peptide substrate                      
              having a CAAX motif, and FPP to determine whether the test substance serves as an                          
              inhibitor for FT activity.                                                                                 
                                                          VI.                                                            
              Barbacid motion (Issue 5)                                                                                  
                     Since we find that Brown does not have a corroborated conception, Brown cannot                      
              prevail.  Barbacid prevails based by being the first to reduce to practice the subject matter              
              of the count.  Since Barbacid will be awarded priority, the Board does not find it necessary               
              to direct attention to the Barbacid motion that the Brown claims are unpatentable under 35                 
              U.S.C. § 135(b).  However, the Board will address the Brown motion against Barbacid for                    
              unpatentablility.                                                                                          
                                                          VII.                                                           
              Brown motion (Issue 4)                                                                                     


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