Ex parte DICK et al. - Page 5




              Appeal No. 1995-2297                                                                                        
              Application No. 07/797,493                                                                                  



              over Reisner, Lubin or Kamel, and remand this application to the examiner for                               
              reconsideration of claims 13 and 14, and to take appropriate action.                                        
                                                     DISCUSSION                                                           
                     In reaching our decision in this appeal, we have given careful consideration to the                  
              appellants’ specification and claims, and to the respective positions articulated by the                    
              appellants and the examiner.  We make reference to the examiner’s Answer (Paper No.                         
              17, mailed July 18, 1994) for the examiner’s reasoning in support of the rejection.  We                     
              further reference appellants’ Brief (Paper No. 16, filed April 21, 1994) for the appellants’                
              arguments in favor of patentability.                                                                        
              I.     The rejection under 35 U.S.C. § 103 over any one of Pollard, Wade or                                 
                     Fohlmeister taken with McCune.                                                                       

              A.     Claims 9, 11 and 12 and drawn to a process for engrafting human                                      
                     hematopoietic cells in an immunodeficient mouse comprising.                                          

                     As appellants point out, each of Pollard, Wade or Fohlmeister teach “interrodentiary                 
              transplants.”  See, Brief, pages 12 and 13.  To overcome the deficiencies in each of the                    
              primary references the examiner applies McCune.  According to the examiner, McCune                          
              “demonstrated the engraftment and differentiation of human tissues in an immune-deficient                   




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