Ex parte ROBERTSON et al. - Page 12




                 Appeal No. 1995-4400                                                                                                                  
                 Application 07/694,302                                                                                                                

                 Maschinenfabrik GmbH v. American Hoist and Derrick Co., 730 F.2d 1452, 1462, 221                                                      
                 USPQ 481, 488 (Fed. Cir. 1984).  Here the examiner has not pointed to anything in the                                                 
                 references which would lead one to the claimed combination and we can find none.  The                                                 
                 only reason to obtain monoclonal antibodies specific for an antigenic determinant of a                                                
                 gp85 envelope precursor protein characteristic of a methanol-fixed F-MuLV infected cell is                                            
                 provided by appellants' disclosure.  It is however impermissible, as examiner has done                                                
                 here, to use appellants' specification as a blueprint to reach the claimed invention from the                                         
                 prior art disclosures. "When prior art references require selective combination by the court                                          
                 to render obvious a subsequent invention, there must be some reason for the combination                                               
                 other than hindsight gleaned from the invention itself."  Uniroyal Inc. v. Rudkin-Wiley Corp.,                                        
















                 837 F.2d 1044, 1051, 5 USPQ2d 1434, 1438 (Fed. Cir. 1988).  Accordingly, we hold that                                                 
                 the examiner has not established a prima facie case of obviousness of the claims.                                                     

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