Ex parte ZALIPSKY et al. - Page 6



              Appeal No. 1995-4572                                                                                        
              Application 08/035,443                                                                                      
                     For all the reasons as discussed above, we find no reasonable suggestion to                          
              combine the relied upon references so as to provide a teaching of a liposome having an                      
              outer layer of polyethylene glycol chains and polymyxin B covalently attached to the                        




              distal ends of the chains, as recited in the instant claims.  Therefore, we reverse both                    
              rejections under 35 U.S.C. § 103.                                                                           
                                                  OTHER ISSUES                                                            
                     From a review of the application file, it is noted that a petition to change the                     
              inventorship by adding Herve Bercovier as an inventor was granted in Paper no. 28,                          
              November 25, 1996.  As of yet, the application file has not been changed to reflect the                     
              addition of the new inventor.   Upon return of the application, the examiner should ensure                  
              that all appropriate PTO records, including the application file, are updated to reflect the                
              correct inventorship.                                                                                       
                     Another issue that the examiner should consider upon return of the application is                    
              application 08/480,332, which is stated to be a continuation-in-part of this application.   An              
              obvious-type double patenting rejection was made in the CIP application between                             
              the claims of the CIP and the claims pending in this application.  The examiner should                      
              review the respective claims and determine whether a reciprocal rejection should be made                    
              in this application.                                                                                        




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