Ex parte BRIDGES et al. - Page 3




              Appeal No. 96-1027                                                                                           
              Application 08/162,288                                                                                       

                     Claims 4, 17-19, and 21-23 are rejected under 35 U.S.C. § 112, first paragraph, "as                   
              the disclosure is enabling only for claims limited to the construct pJR16S."                                 
                     Claims 4, 17-19, and 21-24 are rejected under 35 U.S.C. §103 as being                                 
              unpatentable over "either of van der Krol (Ph.D. Thesis) or Jorgensen et al. taken with Hiatt                
              et al."                                                                                                      

                                                      DISCUSSION                                                           
                     As set forth in the representative claim, the objective of the claimed invention is to                
              modify the expression of a fruit ripening enzyme in a plant cell. In particular (Specification,              
              pp. 1-2), the objective is to inhibit gene expression of the enzymes polygalacturonase and                   
              pectinesterase that cause a fruit's cell wall to change when it ripens.  As indicated in a                   
              number of dependent claims, the invention is particularly directed to tomatos. The claimed                   
              invention accomplishes the fruit enzyme expression modification by transforming the plant                    
              cell with a DNA construct. The DNA construct comprises a recombinant DNA sequence                            
              coding for only a part of the fruit ripening enzyme.                                                         

              Enablement                                                                                                   
                     We first note that two of the three enablement rejections are internally inconsistent.                
              1) With regard to the first enablement rejection, which is directed only to claims 17 and 21-                
              23,  examiner argues (Examiner's Answer, p. 4) that the disclosure is enabling only for                      
              DNA constructs involving polygalacturonase and pectinesterase sequences derived from                         
              tomato.  Claims 4 and 18 are not so limited.  Therefore, to be consistent, the rejection                     


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