Ex parte MORIMOTO et al. - Page 2




          Appeal No. 1996-1080                                                        
          Application No. 07/869,111                                                  

               According to appellants, the invention is directed to a                
          process for selectively methylating the 6-hydroxy position of               
          erythromycin A, and intermediates useful in this process,                   
          which process does not involve the formation of quaternary                  
          salts at the 3'-dimethylamino position (Brief, pages 2-3).                  
          Claims 1 and 3 are illustrative of the subject matter on                    
          appeal and a copy of these claims is attached as an Appendix                
          to this decision.                                                           
               The examiner has relied upon the following references as               
          evidence of obviousness:                                                    
          Faubl et al. (Faubl)           4,640,910          Feb.  3,                  
          1987                                                                        
          Watanabe et al. (Watanabe)     0 158 467          Oct. 16,                  
          1985                                                                        
          (Published European Patent Application)                                     
          Kirk-Othmer, Encyclopedia of Chemical Technology, 3rd ed.,                  
          Vol. 20, pp. 964-65, John Wiley & Sons, 1982.                               
               Claims 1 and 2 stand rejected under 35 U.S.C. § 103 as                 
          unpatentable over Faubl in combination with Watanabe and Kirk-              
          Othmer (Answer, page 2).  Claim 3 stands rejected under 35                  
          U.S.C. § 103 as unpatentable over Watanabe1 in combination                  

               1The last digit is omitted from the citation of Watanabe               
          on page 3 of the Answer.  However, this is a harmless error                 
          since the entire prosecution of this application and parent                 
          application no. 07/094,888 recognize the correct citation of                
                                          2                                           





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