Appeal No. 1996-1204
Application No. 08/090,369
The references relied upon by the examiner are:
Shigemoto et al. (Shigemoto), “Cloning and Expression of a Rat Neuromedin K Receptor
cDNA,” Journal of Biological Chemistry, Vol. 265(2), pp. 623-628 (1990).
Hopkins et al. (Hopkins), “Isolation and Characterization of the Human Lung NK-1
Receptor cDNA,” Biochemical and Biophysical Research Communications, Vol. 180(2),
pp. 1110-1117 (1991).
Gerard et al. (Gerard), “The Human Neurokinin A (Substance K) Receptor,” Journal of
Biological Chemistry, Vol. 265(33), pp. 20455-20462 (1990).
Fraser et al. (Fraser), “Cloning, Sequence Analysis, and Permanent Expression of a
Human " -Adrenergic Receptor in Chinese Hamster Ovary Cells,” Journal of Biological
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Chemistry, vol. 264(20), pp. 11754-11761 (1989).
A reference relied upon by appellants:
Dietl et al. (Dietl), “Phylogeny of Tachykinin Receptor Localization in the Vertebrate Central
Nervous System: Apparent Absence of Neurokinin-2 and Neurokinin-3 Binding Sites in the
Human Brain,” Brain Research, Vol. 539, pp. 211-222 (1991).
Grounds of Rejection
Claims 25-28 and 30 stand rejected under 35 U.S.C. § 103. As evidence of
obviousness, the examiner relies upon Shigemoto, Hopkins, and Gerard.
Claim 29 stands rejected under 35 U.S.C. § 103. As evidence of
obviousness, the examiner relies upon Shigemoto, Hopkins, Gerard, and Fraser.
We reverse.
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