Ex parte TSAO et al. - Page 2




          Appeal No. 1996-2766                                                        
          Application No. 08/258,909                                                  


               According to appellants, the invention is directed to                  
          compositions and dosage forms for cleaning protein and lipid                
          deposits from the lens surface of contact lens by providing a               
          cleaning composition which increases the pH to a basic level                
          using substantially no protein-digesting enzyme or protein-                 
          dissolving surfactant (Brief, pages 2-3).  Claim 15 is                      
          illustrative of the subject matter on appeal and a copy of                  
          this claim is reproduced below:                                             
          15. A solid pH-controlled cleaner dosage form, comprising:                  
               a) a tonicity builder comprising a water-soluble salt                  
          compatible with ocular tissue; and                                          
               b) a pH regulator selected from the group consisting of                
          basic acetates, phosphates, borates, nitrates, sulfates,                    
          tartrates, lactates, carbonates, bicarbonates, and mixtures                 
          thereof, whereby dissolution of said pH regulator in an                     
          aqueous environment results in a protein cleaning composition               
          having a pH of 7.5 to 11.5,                                                 
               wherein said composition includes substantially no                     
          protein-digesting enzyme and wherein a protein-dissolving                   
          effective amount of surfactant is absent from said                          
          composition.                                                                
               The examiner has relied upon the following references as               
          evidence of obviousness:                                                    
          Fu                            4,323,467          Apr. 6, 1982               
          Davies et al. (Davies)        4,863,627          Sep. 5, 1989               


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