Ex parte CHEN - Page 6




          Appeal No. 1996-3017                                                         
          Application No. 08/851,810                                                   


          ordinary skill in the art would have had a reasonable                        
          expectation of successfully isolating the product alkyl-                     
          pyrazine from the aqueous medium utilizing the                               
          recrystallization method disclosed by Bonzom.  Appellant has                 
          not apprised us of any reason, and we are not aware of one,                  
          why one of ordinary skill in the art would have been dissuaded               
          from applying Bonzom's recrystallization technique to an                     
          aqueous medium comprising an alkyl-pyrazine simply because the               
          reactant mixture may contain amounts of an acetylene starting                
          reactant rather than an acyloin starting reactant.  Also,                    
          since distillation, extraction and recrystallization are all                 
          conventional techniques used in the art to isolate compounds                 
          from aqueous medium, we are satisfied that one of ordinary                   
          skill in the art would have found it obvious to simply                       
          determine which of the known techniques produce the optimum                  
          yield without the need to resort to undue experimentation.                   
          Compare In re Boesch,                                                        
          617 F.2d 272, 276, 205 USPQ 215, 219 (CCPA 1980).  We find no                
          flaw in the following reasoning of the examiner:                             
               The different modes of purification would be                            
               considered alternately and even sequentially usable                     
               since isolation is a separate consideration for the                     
               synthetic chemist once a product mixture is obtained                    
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