Ex parte WEIS-FOGH - Page 2




                 Appeal No. 1997-0875                                                                                                                   
                 Application No. 07/998,128                                                                                                             


                                   55.  A tissue repair promoting composition comprising tissue repair                                                  
                          promoting substances isolated from plasma and tissue repair promoting                                                         
                          substances isolated from platelets, the tissue repair promoting substances                                                    
                          isolated from plasma including at least fibrinogen, the composition being                                                     
                          substantially free of fibrin.                                                                                                 
                                   68.  The composition of Claim 55 wherein the tissue repair promoting                                                 
                          substances are isolated from the plasma and platelets of a single human or                                                    
                          animal.                                                                                                                       
                          The references relied on by the examiner are:                                                                                 
                 Schwarz et al. (Schwarz)                                       4,377,572                  Mar. 22, 1983                                
                 Zimmerman et al. (Zimmerman)                                   4,453,939                  Jun.  12, 1984                               
                 Sundsmo et al. (Sundsmo)                              4,760,131                  Jul.   26, 1988                                       
                 Mann                                                           2 146 335                  Apr. 17, 1985                                
                 (UK Patent Application)                                                                                                                
                 Rose et al. (Rose)                                    WO 86/01814                         Mar. 27, 1986                                
                 (International Patent Application)                                                                                                     
                 Senior et al. (Senior), "Chemotactic Activity of Platelet Alpha Granule Proteins for                                                   
                 Fibroblasts," The Journal of Cell Biology, Vol. 96, pp. 382-385 (February 1983)                                                        
                          A reference relied on by appellant (brief, p. 7) is:                                                                          
                 Knighton                                                       5,165,938                  Nov. 24, 1992                                
                                                                       ISSUE                                                                            
                          Claims 55-64, 67 and 68 stand rejected under 35 U.S.C. § 103 as being                                                         
                 unpatentable over Schwarz, Sundsmo, Zimmerman, Mann, Senior and Rose.                                                                  
                          We reverse.                                                                                                                   




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