Ex parte CHIN et al. - Page 11




          Appeal No. 1997-1301                                                        
          Application No. 08/079,310                                                  


               The examiner has not presented any convincing evidence or              
          reasoning as to why the proposed substitution at the alpha                  
          carbon of the benzyl group would facilitate the reaction set                
          forth in Scheme III of Reichmanis.  The heterocyclic                        
          intermediate in Scheme III of Reichmanis is formed by removal               
          of a hydrogen atom from the alpha carbon of the benzyl group                
          (page 398).  The examiner has not explained or presented                    
          reasoning why an electron-withdrawing group would not make                  
          removal of this hydrogen more difficult, rather than                        
          facilitate its removal (see the Reply Brief, page 10).                      
               For the foregoing reasons and those presented in the                   
          Reply Brief, we determine that the examiner has not                         
          established a prima facie case of obviousness.  In light of                 
          this determination, we need not consider the sufficiency of                 
          appellants’ evidence of unobviousness (e.g., the Houlihan                   
          Declaration under 37 CFR                                                    
          § 1.132 dated Jan. 13, 1997, Paper No. 22).  In re Geiger, 815              
          F.2d 686, 688, 2 USPQ2d 1276, 1278 (Fed. Cir. 1987).                        
          Accordingly, the examiner’s rejection of claims 1-5 under                   
          35 U.S.C. § 103 as unpatentable over Houlihan in view of                    


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