Ex parte DILLARD et al. - Page 2




          Appeal No. 1997-2184                                                        
          Application 08/278,441                                                      

          non-elected invention, 37 C.F.R. § 1.142(b), and, accordingly,              
          form no issue in this appeal.                                               




                                    THE INVENTION                                     
               The appealed subject matter is directed to a genus of                  
          compounds which may be broadly characterized as indene-1-                   
          acetamides.  According to appellants, the compounds are useful              
          for the general treatment of conditions induced or maintained               
          by overproduction of the enzyme human non-pancreatic secretory              
          phospholipase A  or "sPLA ".  Such conditions include septic2        2                                                   
          shock, adult respiratory distress syndrome, pancreatitis,                   
          trauma, bronchial asthma, allergic rhinitis and rheumatoid                  
          arthritis.                                                                  
               Claims 1, 11 and 14 are believed to be adequately                      
          representative of the appealed subject matter and are                       
          reproduced below for a more facile understanding of                         
          appellants' invention.                                                      
               Claim 1. An indene-1-acetamide compound or a                           
               pharmaceutically acceptable salt, solvate or prodrug                   
               derivative thereof; wherein said compound is                           
               represented by the formula (I);                                        


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