Ex Parte YAMAMOTO et al - Page 19




          Appeal No. 1998-1418                                                       
          Application 08/313,249                                                     



          the ‘straw’ tip of the pump shaft via routine experimentation”             
          (final rejection, pg. 7).  Appellants merely argue that none of            
          the applied prior art teaches or suggests that the distance                
          between the tube/pipe and the vessel side surface is about                 
          2-3 mm.  To this, the examiner points out on page 7 of the                 
          answer, that appellants fail to address the rejection with                 
          regard to determining the optimum arrangement of the elements              
          due to routine experimentation.  We agree with the examiner that           
          one of ordinary skill in this art would have been led by the               
          teachings of Dobilas, Junghans, Sukhin and Hughes to arrive at             
          the spacing of “about 2-3 mm” as an optimum distance between the           
          vessel side wall and the lower end of the pump shaft so as to              
          maximize use of substantially all of the medicant, as expressly            
          indicated in Hughes.  More specifically, we note that the surface          
          14 of Hughes can be considered a side surface to the degree                
          appellants disclose side surface 65.  Common sense would have led          
          an ordinarily skilled artisan to provide a reasonable distance             
          between the side surface and the bottom of the pump shaft close            
          enough such that all of the medicant can be utilized.  However,            
          the side surface and the pump shaft should also not come                   
          into contact with one another in order to prevent any obstruction          




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