Ex parte ITO et al. - Page 2




                 Appeal No. 1998-2836                                                                                                                   
                 Application No. 08/453,211                                                                                                             


                          The subject matter on appeal is directed to a bone                                                                            
                 substitute material or sheet and to a method of using a bone                                                                           
                 substitute material wherein the bone substitute material is                                                                            
                 “formed by kneading a powdery mixture of animal bone powder                                                                            
                 and a divalent metal compound together with chitosan sol which                                                                         
                 is prepared by dissolving chitosan by acid” (specification, p.                                                                         
                 4).  Claim 1 is illustrative of the subject matter on appeal                                                                           
                 and is reproduced below:1                                                                                                              
                 1.  A bone substitute material comprising animal bone powder.                                                                          
                          The prior art references of record relied upon by the                                                                         
                 examiner in rejecting the appealed claims are:2                                                                                        

                          1We note that the amendment after final rejection filed                                                                       
                 on October 11, 1996 (Paper No. 9) has been clerically entered                                                                          
                 in error. See Paper Nos. 10 and 22. The error should be                                                                                
                 corrected upon return of the application to the jurisdiction                                                                           
                 of the examiner.                                                                                                                       
                          2We call the following documents (copies enclosed) to the                                                                     
                 examiner’s and to the appellants’ attention:                                                                                           
                          Bell (U.S. Patent No. 4,485,097) teaching a bone-                                                                             
                 equivalent and a method for preparation thereof comprising,                                                                            
                 inter alia, demineralized bone powder.  See, e.g., col. 6, l.                                                                          
                 9 to col. 7, l. 12 and claim 1.                                                                                                        
                          O’Leary et al. (U.S. Patent No. 5,290,558, cited in                                                                           
                 grandparent application No. 08/015,918) teaching a                                                                                     
                 demineralized bone powder composition disclosed as being                                                                               
                                                                                                            (continued...)                              
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