PITHA V. MULLER et al. - Page 25




          Interference 102,413                                      Page 25           
          Pitha v. Muller                                                             
          testosterone.  The experiment took place no later than                      
          September 9, 1982, which is the date indicated on PX-24-45.                 
               The count requires an intrinsically amorphous mixture of               
          cyclodextrin derivatives which are water soluble and capable                
          of forming inclusion complexes with drugs in water.  The                    
          product C-70 was not described in terms of it’s amorphous                   
          nature.  Pitha did not direct us to testimony which                         
          establishes (1) the amorphous properties of this product or                 
          (2)that the product contained more than one cyclodextrin                    
          derivative.  In fact, page C-70, PX-23-82, does not describe                
          the substance formed.  For the above reasons, and because                   
          proof of the existence of a physical embodiment within the                  
          scope of the count has not been shown, we cannot rely on the                
          experimental evidentiary data described on page C-70 to                     
          establish an actual reduction to practice of an embodiment                  
          within the scope of the count.                                              
               4.  The Research of Dr. Lajos Szente.                                  
               PX-19 is a reproduction of the laboratory notebook of                  
          Dr. Lajos Szente.  According to the first page of the notebook              
          (PX-19-001), the entries in the notebook occurred between the               
          dates of May 15, 1981 to December 28, 1981.  These experiments              
          all occurred no later than December 21, 1983, Muller’s                      
          accorded benefit date.                                                      





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