Ex parte JANOFF et al. - Page 8


              Appeal No. 2001-1245                                                                                     
              Application 08/430,661                                                                                   
                     Heyne describes a procedure similar to that of Moro.  As seen from page 4 of the                  
              translation, the active agents are added to the solution of substances which will form the               
              liposome, apparently either directly in the case of lipophilic active substances or as an                
              aqueous solution in the case of hydrophilic active substances.  Suffice it to say the                    
              examiner has not established that Heyne describes the sequence of steps required by                      
              claim 77 on appeal or provided sufficient reasons why one of ordinary skill in the art                   
              would have found it obvious to alter the sequence of steps described in Fukushima in                     
              order to arrive at the subject matter of claim 77.                                                       
                     The examiner's rejection as it is based on the combination of Fukushima and                       
              Moro or Fukushima and Heyne is reversed.                                                                 
                     The decision of the examiner is reversed.                                                         

                                                    REVERSED                                                           






                                                                             )                                         
                                   Sherman D. Winters                       )                                         
                                   Administrative Patent Judge               )                                         
                                                                             )                                         
                                                                             )                                         
                                                                             ) BOARD OF PATENT                         
                                   William F. Smith                         )                                         
                                   Administrative Patent Judge               )   APPEALS AND                           
                                                                             )                                         
                                                                             ) INTERFERENCES                           
                                                                             )                                         
                                   Linda R. Poteate                         )                                         
                                   Administrative Patent Judge               )                                         




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