Appeal No. 1997-3511
Application No. 08/233,663
Claims 1, 9, 14, 19, and 29 are illustrative of the claims on appeal and are
reproduced below:
1. A composition comprising factor IX, glycine, a cryoprotectant, and a
surfactant.
9. The composition of claim 1, further comprising calcium chloride.
14. The composition of claim 1, further comprising a buffering agent.
19. A composition comprising factor IX, glycine, a surfactant, and a member
selected from the group consisting of a buffering agent and a cryoprotectant.
29. The composition of claim 19, wherein said surfactant is polysorbate, wherein
said cryoprotectant is sucrose and further comprising calcium chloride.
The references relied on by the examiner are listed below:
Zolton et al. (Zolton) 4,597,966 Jul. 1, 1986
Bhattacharva et al. (Bhattacharva)5,288,853 Feb. 22, 1994
Mathews et al. (Mathews) 4,952,675 Aug. 28, 1990
Schwinn DE 4,001,451 Aug. 1, 1991
(Abstract No. 91-237793/32)
Wang et al. (Wang), "Parenteral Formulations of Proteins and Peptides: Stability
and Stabilizers," J. Parenteral Sci. and Tech., Vol. 42(S), pp S3-S26 (1988)
2
Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 Next
Last modified: November 3, 2007