Ex Parte SRINIVASAN et al - Page 2




              Appeal No. 1997-4379                                                                                        
              Application No. 08/278,437                                                                                  
              Appendix A, attached.                                                                                       
                     The references relied on by the examiner are:                                                        
              Dean et al. (Dean)                        5,225,180                   Jul. 6, 1993                        
              Jost et al. (Jost), “Amino Acids and Peptides. C.  The Effect of the Presence of Sulphur                    
              Atoms on the Biological Activity of Oxytocin; Synthesis of Deamino-Carba6-Oxytocin                          
              and Deamino-Dicarba-Oxytocin,” Collection Czechoslov. Chem. Commun., Vol. 36,                               
              pp. 234-245 (1971)                                                                                          
              Rivier et al. (Rivier), “Biological Action of Somatostatin,” Rec. Progm. Horm. Res.,                        
              Vol. 31, pp. 369-371 (1975)                                                                                 
              Edwards et al. (Edwards), “In Vitro Activity Profiles of Cyclic and Linear Enkephalin                       
              Pseudopeptide Analogs,” Biochemical and Biophysical Researcy Communication,                                 
              Vol. 136, No.2, pp.730-736 (1986)                                                                           
              Mather et al. (Mather), “What Lessons for Antibody-Mediated Targeting?,” Cell                               
              Biophysics, Vol. 21, pp. 93-107 (1992)                                                                      
                     The references relied upon by appellants are:                                                        
              Blake et al. (Blake)                5,439,792                  Aug. 8, 1995                                
              Belinka, Jr. et al. (Belinka)       5,449,761                  Sep. 12, 1995                               
                                                 Grounds of Rejection                                                     
                     The appealed claims stand rejected as follows:                                                       
              1.      Claims 1 through 5 and 14 through 18 under 35 U.S.C. § 112, first paragraph,                        
                      as based on a non-enabling disclosure.                                                              
              2.      Claims 1 through 5 and 14 through 18 under 35 U.S.C. § 103.  As evidence of                         
                      obviousness, the examiner relies on Dean, Edwards and Jost.                                         
                     On consideration of the record, we reverse the rejection under 35 U.S.C. § 112,                      
              first paragraph and vacate the rejection under 35 U.S.C. § 103.                                             



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