Ex parte RASMUSSEN et al. - Page 13


                  Appeal No.  1998-1719                                                                                      
                  Application No.  08/442,603                                                                                
                  claimed cells lies their ability to produce recombinant glucocerebrosidase, and                            
                  since the improved property relates to production of recombinant                                           
                  glucocerebrosidase, the unexpected property relates to a significant aspect of the                         
                  claimed invention.  Therefore, I find it sufficient to overcome the prima facie                            
                  obviousness suggested by the prior art.                                                                    
                         In sum, I find no defect in the examiner’s prima facie case.  I would, however,                     
                  reverse on the basis of Appellants’ evidence of unexpected results.                                        


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                                        Eric Grimes                         )   APPEALS AND                                 
                                        Administrative Patent Judge          )                                               
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