Ex parte VINOGRADOV et al. - Page 5


                       Appeal No.  1998-2107                                                                                                                     
                       Application No.  08/137,624                                                                                                               
                       Rejection #4:                                                                                                                             
                                 According to the examiner (Answer, page 6):                                                                                     
                                                    The instant invention is drawn to a reaction of halogen                                                      
                                          (as in COCl) with [an] OH group.  This is a text book reaction.                                                        
                                          Morrision and Boyd describes [sic] a reaction of acid chloride                                                         
                                          and alcohol.  The difference is that the instant invention is                                                          
                                          drawn to porphyrin and glycol derivatives.  However, it would                                                          
                                          have been obvious for one skilled in the art to apply the                                                              
                                          reaction as taught by the prior art, to porphyrin and PEG                                                              
                                          derivatives and obtain results similar to the instant invention,                                                       
                                          because of the similarity of the reacting group.                                                                       
                                                    The claimed process is entirely analogous to and                                                             
                                          therefore obvious over [the] process in [the] prior art, since the                                                     
                                          same functional groups react under routine conditions to give a                                                        
                                          predictable product.  It is also obvious that one skilled in the art                                                   
                                          recognized thionyl chloride and oxalyl chloride are well-known                                                         
                                          reagents to prepare acid chlorides.                                                                                    
                                 In response appellants argue (Brief, page 18) that:                                                                             
                                          The Examiner, however, has based his opinion on erroneous                                                              
                                          and incorrect law.  In particular, the Examiner’s per se                                                               
                                          standards that “novel reactants will not alone render the                                                              
                                          process unobvious” and that “[t]he question of patentability for                                                       
                                          a process claim is whether the reaction itself is novel and                                                            
                                          unobvious” are clearly incorrect.  On this issue, the Board’s                                                          
                                          attention is respectfully directed to In re Ochiai, 71 F.3d 1565,                                                      
                                          37 USPQ2d 1127 (Fed. Cir. 1995).                                                                                       
                                 The examiner responds (Answer, pages 9-10) to appellants’ argument as                                                           
                       follows:                                                                                                                                  
                                                    In re Ochiai [sic] did not overturn any prior case law,                                                      
                                          certainly not In re Albertson, [sic] 141 USPQ 730.  The                                                                
                                          decision merely says: do not cite case law to me, argue the                                                            
                                          chemistry.  Note how close the prior art is to what is being                                                           
                                          claimed here, in the manner of Graham vs. John Deere Co.,                                                              
                                          [sic] (USSC 1966), 383 US1 [sic]; 148 USPQ 459 which was                                                               
                                          done here.                                                                                                             
                                                                                                                                                                 
                       6 We note that, in contrast to the examiner’s statement of the rejection, we find no                                                      
                       rejection of claims 22-24 and 26-59 over Vanderkooi “above.”                                                                              

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