WALLACE et al. v. HUBBARD - Page 11



          Interference No. 103,570                                                    

          that the particles be “substantially non-resorbable” as required            
          by Hubbard claim 21.  In this regard, we note that none of the              
          variety of exemplary biomaterials listed in Wallace (col. 3, ll.            
          1-11) appear to be ceramic materials.                                       
                                 Draenert (WX-14)                                     
               We entirely agree with Hubbard that Draenert is not an                 
          effective reference against the claims in question since Draenert           
          teaches away from using “substantially non-resorbable” particles.           
          Indeed, while Draenert uses particles which are spherical in                
          shape, Draenert requires that they be highly porous and                     
          “absorbable in the body” in order to provide “channels into which           
          the bone tissue can grow” (col. 1, ll. 10-20; col. 2, ll. 22-27;            
          col. 3, ll. 17-19).  This is in contrast to Hubbard’s ceramic               
          matrix particles which are made “substantially non-resorbable”              
          by sintering to provide a scaffold or lattice for soft tissue               
          growth at the augmentation site (Hubbard specification: p. 7,               
          l. 31-p. 8, l. 7).  Thus, the absorbable particles of Draenert              
          serve a fundamentally different purpose than the substantially              
          non-resorbable particles of Hubbard.  These fundamental                     
          differences are more fully explained by Poser (HR 138-139) and              
          Devine (HR 108-111).                                                        


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