Ex Parte DAROUICHE - Page 2


                 Appeal No. 2001-0599                                                         Page 2                    
                 Application No. 08/555,198                                                                             

                        The examiner relies on the following references:                                                
                 Kitrilakis et al. (Kitrilakis)            3,699,956             Oct. 24, 1972                          
                 Sakamoto et al. (Sakamoto)                4,539,234             Sep. 03, 1985                          
                 Lee                                     4,723,950             Feb. 09, 1988                          
                 Goldberg et al. (Goldberg)                5,100,689             Mar. 31, 1992                          
                 Dangman et al. (Dangman)                  5,335,373             Aug. 09, 1994                          

                        Claims 23-26, 30, and 35-37 stand rejected under 35 U.S.C. § 102(b) as                          
                 anticipated by Sakamoto.                                                                               
                        Claims 23-26, 30, 35, and 36 stand rejected under 35 U.S.C. § 102(b) as                         
                 anticipated by Lee.                                                                                    
                        Claims 23-27, 30, and 35-41 stand rejected under 35 U.S.C. § 103 as                             
                 obvious in view of Kitrilakis, Dangman, and Goldberg.                                                  
                        We affirm in part and reverse in part.                                                          
                                                     Background                                                         
                        The specification discloses that implanted medical devices are a common                         
                 source of bacterial and fungal infections, and that various methods have been                          
                 tried to prevent such infections, including coating the implanted devices with                         
                 antibiotics.  See pages 3-5.  “However, although antibiotic-coated medical                             
                 devices, such as those coated with minocycline and rifampicin, are very effective                      
                 against Staphylococci, their efficacy against gram-negative bacteria and                               
                 [C]andida is limited.”  Id., page 5.                                                                   
                        The specification discloses that coating medical devices with antiseptics,                      
                 rather than antibiotics, provides broader protection against infectious agents.                        
                 The coated medical device may be, e.g., a urinary catheter or vascular catheter.                       






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