Ex Parte MARTIN - Page 1



                           The opinion in support of the decision being entered today was not written                   
                                   for publication and is not binding precedent of the Board.                           
                                                                                           Paper No. 23                 
                         UNITED STATES PATENT AND TRADEMARK OFFICE                                                      
                                                    __________                                                          

                              BEFORE THE BOARD OF PATENT APPEALS                                                        
                                             AND INTERFERENCES                                                          
                                                     __________                                                         
                                             Ex parte MARK T. MARTIN                                                    
                                                     __________                                                         
                                                Appeal No. 2001-0940                                                    
                                             Application No. 08/467,712                                                 
                                                     __________                                                         
                                                      ON BRIEF                                                          
                                                     __________                                                         
              Before WINTERS, WILLIAM F. SMITH, SCHEINER, Administrative Patent Judges.                                 
              SCHEINER, Administrative Patent Judge.                                                                    
                                               DECISION ON APPEAL                                                       
                     This is an appeal under 35 U.S.C. § 134 from the final rejection of claims 12-17,                  
              all the claims remaining in the application.  Claim 12 is representative of the subject                   
              matter on appeal and reads as follows:                                                                    
                     12.  A method for the determination of the concentration of an enzyme substrate                    
              present in a specimen, comprising the steps of:                                                           
                     (a) contacting said specimen with an oxidoreductase conjugate under conditions                     
              which permit the oxidation of the enzyme substrate, said oxidoreductase conjugate                         
              comprising a co-factor and a species capable of generating an electrochemiluminescent                     
              signal separately linked in close proximity to an active site of said oxidoreductase in a                 
              manner which permits their electrochemical interaction with each other and a substrate                    
              also in close proximity to the active site;                                                               
                     (b) measuring the change in electrochemiluminescence from a base reading; and                      
                     (c) determining the concentration of enzymatic substrate based on the measured                     
              change in electrochemiluminescent signal.                                                                 
                     The references relied on by the examiner are:                                                      
              Nacamulli et al. (Nacamulli)              5,527,710                   Jun. 18, 1996                       



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