Ex Parte TAKLE et al - Page 3


                 Appeal No.  2001-1705                                                       Page 3                  
                 Application No.  08/616,141                                                                         
                 Yu et al. (Yu) “A Hairpin Ribozyme Inhibits Expression of Diverse Strains of                        
                 Human Immunodeficiency Virus Type 1,” Proc. Natl. Acad. Sci, Vol. 90                                
                 pp. 6340-6344 (1993)                                                                                
                                           GROUNDS OF REJECTION                                                      
                        Claim 31 stands rejected under 35 U.S.C. § 112, first paragraph, as being                    
                 based on an insufficient disclosure to support or enable the claimed invention.                     
                        Claims 1, 2, 5, 6, 19, 20, 23 and 30 stand rejected under 35 U.S.C.                          
                 § 102(b) as anticipated by Cannon                                                                   
                        Claims 1-8, 11, 12, 19-25 and 31 stand rejected under 35 U.S.C. § 103 as                     
                 being unpatentable over Dixon in view of any one of Yu, Leonetti or Lisziewicz.                     
                        Claims 1-8, 11-13, 19-24 and 31 stand rejected under 35 U.S.C. § 103 as                      
                 being unpatentable over Doan and Offensperger.                                                      
                        Claims 26-29 stand rejected under 35 U.S.C. § 103 as being unpatentable                      
                 over Dixon, Yuan, Offensperger and Korba.                                                           
                        We reverse.                                                                                  
                                                   DISCUSSION                                                        
                 THE REJECTION UNDER 35 U.S.C. § 112, FIRST PARAGRAPH:                                               
                        To satisfy the enablement requirement of 35 U.S.C. § 112, first                              
                 paragraph, a patent application must adequately disclose the claimed invention                      
                 so as to enable a person skilled in the art to practice the invention at the time the               
                 application was filed without undue experimentation.  Enzo Biochem, Inc. v.                         
                 Calgene, Inc., 188 F.3d 1362, 1371-72, 52 USPQ2d 1129, 1136                                         
                 (Fed. Cir. 1999).  We note, however, that “nothing more than objective                              
                 enablement is required, and therefore it is irrelevant whether this teaching is                     







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