Ex Parte LIPTON - Page 7


                 Appeal No.  2001-1905                                                          Page 7                  
                 Application No.  08/245,827                                                                            
                 oxidizing agent at the in vivo site of the NMDA receptor….”  The examiner                              
                 provides no evidence to dispute this fact, and we find the examiner’s argument                         
                 (Answer, page 12) that the claims do not recite the term “equilibrium” lacks merit.                    
                        On reflection, we are not persuaded by the examiner’s conclusions.                              
                 Based on the foregoing discussion, we find that the examiner failed to meet his                        
                 burden of establishing a prima facie case of non-enablement.  Accordingly, we                          
                 reverse the rejection of claim 11 and 13-15 under 35 U.S.C. § 112, first                               
                 paragraph.                                                                                             
                        Having determined that the examiner has not established a prima facie                           
                 case of obviousness, we find it unnecessary to discuss the Declaration evidence                        
                 relied on by appellants to rebut any such prima facie case.  Furthermore, we                           
                 recommend the examiner review Enzo Biochem, Inc. v. Calgene, Inc., 188 F.3d                            
                 1362, 1371, 52 USPQ2d 1129,1136 (Fed. Cir. 1999), wherein our appellate                                
                 reviewing court provided a model analysis of enablement issues and illustrated                         






















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