Ex Parte KEITH et al - Page 5




          Appeal No. 2002-0396                                                          
          Application No. 08/331,280                                                    


               Pray discloses a microtube having a relatively stiffer                   
          proximal end and a relatively more flexible distal end,                       
          comprising an inner cured resin layer (24), a braid layer (52)                
          over the inner cured resin layer, and an outer cured resin                    
          layer (54) over and encasing the braid layer, wherein the braid               
          layer is woven in a weave having relatively fewer picks per inch              
          at the proximate end and relatively more picks per inch at the                
          distal end (col. 2, lines 31-34; col. 3, lines 22-30; col. 3,                 
          line 66 - col. 4, line 37; col. 10, lines 13-14).                             
               The second supplemental declaration under 37 CFR § 1.131                 
          shows that, no later than November 1992, the appellants were in               
          possession of a microtube having an inner cured resin layer, a                
          braid layer over the inner cured resin layer, and an outer cured              
          resin layer over and encasing the braid layer, wherein the braid              
          pick count varies over the length of the catheter to provide                  
          increased flexibility from the proximal end to the distal end                 
          (declaration exhibits D, E, F, G, H, J, K, L, N and O).                       
               The declaration exhibits do not show fewer picks per inch at             














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