Ex Parte BRUCK et al - Page 11




          Appeal No. 2002-0984                                                        
          Application 09/246,179                                                      

               the opportunity to make a challenge. (citations omitted)               
               Where the appellant has failed to challenge a fact                     
               judicially noticed and it is clear that he has been amply              
               apprised of such finding so as to have the opportunity to              
               make such challenge, the board's finding will be considered            
               conclusive by this court. (citations omitted)                          
          The examiner's action here is exacerbated because his findings,             
          disguised in the nature of the "Examiner's Notice", have not been           
          shown to be facts, have not been supported by citations to any              
          reference, have been challenged by appellants and go to the very            
          limitations in the claimed process which may be considered to               
          distinguish the claimed process from the prior art. Our reasoning           
          in support of this statement follow immediately below.                      
               We find each of the Doyle references on which the examiner             
          has relied is evidence which establishes that IR-ATR spectroscopy           
          has been used to monitor a variety of chemical reactions,                   
          including reactions conducted in "kettles" which are closed                 
          vessels in which the reactants to be reacted are contacted and              
          stirred. The disclosure in Berard is extremely similar to that in           
          the Doyle references. Further, Berard includes two specific                 
          examples of monitoring the progress of chemical reactions using             
          IR spectroscopy, specifically optical fiber cylindrical internal            
          reflectance. In one example the conversion of an aldehyde to the            
          corresponding alcohol was measured by measuring instantaneously             
          during the reaction the concentration of the aldehyde versus the            
          concentration of the alcohol. In another example the preparation            

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