KHAVARI et al. V. TANG et al. - Page 2





            Interference No. 104,696 Paper 65                                                                              
            Khavari v. Tang Page 2                                                                                         
                                              R-4TERFERENCE-IN-FACT                                                        
            [11 Khavari moved forjudgment that no interference-in-fact existed (Paper 24). The motion                      
                    was denied in an interlocutory decision of a single administrative patent judge (Paper 28).            
                    Khavari has requested reconsideration (Paper 35). Tang opposes the request for                         
                    reconsideration (Paper 54).                                                                            
             [2] Tang has also requested judgment of no interference-in-fact (Paper 42).                                   
             [3] Count 1, the sole count, is:                                                                              
                                  The method of Khavari claim I or of Tang claim 167.                                      
             [41 Khavari claim I is:                                                                                       
                           A method for inducing an immune response in a vertebrate, the method                            
                    comprising the steps of:                                                                               
                                   applying topically to skin of a subject an immunogen-encoding                           
                           polynucleotide in an amount sufficient for uptake by a skin cell and                            
                           sufficient for expression of the immunogen-encoding polynucleotide and                          
                           induction of an immune response, wherein the skin to which the                                  
                           polynucleotide is applied comprises hair and is not treated with a chemical                     
                           or mechanical irritant, and wherein the polynucleotide is operably linked                       
                           to a promoter, and is not contained within a viral particle.                                    
             [5] Tang claim 167 is:                                                                                        
                           A method of non-invasively inducing a protective systemic immune                                
                    response, comprising topically administering, a DNA vector that encodes a gene                         
                    of interest and expresses a protein encoded by the gene of interest, to the skin of a                  
                    mammal, in an effective amount to induce said protective systemic immune                               
                    response to said protein, wherein a systemic immune response to said protein is                        
                    induced in said mammal; and, whereby said protein comprises an antigen or                              
                    immunogenic fragment thereof.                                                                          
             [61 Khavari argues (Paper 24 at 3) that its claim I requires that "the skin to which the                      
                    polynucleotide is applied comprises hair and is not treated with a chemical or mechanical              







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