Ex Parte ROLLINS et al - Page 18


                   Appeal No. 2001-0869                                                                 Page 18                       
                   Application No. 08/453,347                                                                                         

                   JE/MCP-1 protein itself or cells that naturally express JE/MCP-1.  As discussed                                    
                   above, Appellants’ ‘078 patent does not describe methods of administering cells                                    
                   that naturally express JE/MCP-1.  Therefore, the ‘078 patent’s claims 5 and 6 are                                  
                   most reasonably construed as directed to administration of cells that have been                                    
                   genetically engineered to express JE/MCP-1, such as the cells described in the                                     
                   ‘078 patent at, e.g., col. 6, line 67, to col. 8, line 3.                                                          
                           The ‘884 interference involved claims 1-5 of Appellants’ Patent 5,212,073.                                 
                   Those claims are directed to DNA encoding JE/MCP-1 (claim 1), a vector                                             
                   comprising such DNA (claim 2), a mammalian or bacterial cell transformed with                                      
                   such a vector (claims 4 and 5), and a method of making JE/MCP-1 (claim 3).                                         
                   The count in the ‘884 interference read as follows:  “An isolated and purified DNA                                 
                   molecular [sic] encoding human JE protein or MCP-1 protein, said protein                                           
                   possessing monocyte chemoattractant activity.”  See Paper No. 1 in the ‘884                                        
                   interference.  Thus, neither the count nor any of Appellants’ involved claims in                                   
                   the ‘884 interference were directed to a method of treatment.  Appellants’                                         
                   favorable judgment in the ‘884 interference thus does not preclude rejection of                                    
                   the present claims on the basis of the adverse judgment in the ‘998 interference.                                  
                           To the extent that Appellants’ position is that the present claims should be                               
                   considered to correspond to the count of the ‘884 interference (which Appellants                                   
                   won), we disagree.  As discussed above, claims 5 and 6 of Appellants’ ‘078 patent                                  
                   should be construed as directed to methods of treatment using genetically                                          
                   engineered cells.  Thus, it appears that Appellants could have moved to have                                       
                   these claims designated as not corresponding to the count of the ‘998 interference                                 





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