Ex Parte HAGER et al - Page 3




             Appeal No. 2001-1265                                                                                    
             Application No. 08/612,074                                                                              
             Examiner's Answer for the examiner=s complete reasoning in support of the rejection,                    
             and to the appellants= Brief for the appellants= arguments thereagainst. As a                           
             consequence of our review, we make the determinations which follow.                                     


             35 U.S.C. ' 103                                                                                         
                    Claims 25-36 stand rejected under 35 U.S.C. ' 103(a) as obvious over Weder 1,                    
             Weder 2 or Lichtenberg, by themselves or in combination.                                                
                    In rejecting claims under 35 U.S.C. ' 103, the examiner bears the initial burden                 
             of presenting a prima facie case of obviousness.  See In re Rijckaert, 9 F.3d 1531,                     
             1532, 28 USPQ2d 1955, 1956 (Fed. Cir. 1993).  A prima facie case of obviousness is                      
             established when the teachings from the prior art itself would appear to have suggested                 
             the claimed subject matter to a person of ordinary skill in the art.  In re Bell, 991 F.2d              
             781, 783, 26 USPQ2d 1529, 1531 (Fed. Cir. 1993).  An obviousness analysis requires                      
             that the prior art both suggest the claimed subject matter and reveals a reasonable                     
             expectation of success to one reasonably skilled in the art.  In re Vaeck, 947 F.2d 488,                
             493, 20 USPQ2d 1438, 1442 (Fed. Cir. 1991).                                                             


                    It is the examiner=s position that (Answer, page 4):                                             
                    Weder discloses a liposome system containing phospholipid and a bile                             
                    salt, sodium cholate (note the abstract, columns 3-10 and example 1).                            
                    Although the ratios of phospholipid to bile salts taught by Weder are                            
                    different from the instant ratios, it is deemed obvious to an artisan to                         


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