Ex Parte MACLEOD - Page 4


                   Appeal No.  2001-1651                                                                  Page 4                     
                   Application No.  09/238,972                                                                                       
                           invention guards against the inventor’s overreaching by insisting                                         
                           that he recount his invention in such detail that his future claims                                       
                           can be determined to be encompassed within his original                                                   
                           creation”).  The possession test requires assessment from the                                             
                           viewpoint of one of skill in the art.  Id. at 1563-64 (“the applicant                                     
                           must ... convey with reasonable clarity to those skilled in the art                                       
                           that, as of the filing date sought, he or she was in possession of the                                    
                           invention”) (emphasis in original); Union Oil Co. of Cal. v. Atlantic                                     
                           Richfield Co., 208 F.3d 989, 997, 54 USPQ2d 1227, 1232 (Fed.                                              
                           Cir. 2000) (“The written description requirement does not require                                         
                           the applicant ‘to describe exactly the subject matter claimed,                                            
                           [instead] the description must clearly allow persons of ordinary skill                                    
                           in the art to recognize that [he or she] invented what is claimed’”)                                      
                           (citation omitted).  In Enzo [Biochem, Inc. v. Gen-Probe, Inc., 296                                       
                           F.3d 1316, 63 USPQ2d 1609 (Fed. Cir. 2002)] and Amgen[ Inc. v.                                            
                           Hoechst Marion Roussel Inc., 314 F.3d 1313, 1330, 65 USPQ2d                                               
                           1385, 1397 (Fed. Cir. 2003)], the record showed that the                                                  
                           specification that taught one of skill in the art to make and use an                                      
                           invention also convinced that artisan that the inventor possessed                                         
                           the invention.  Similarly in this case, the Lilly [Regents of the                                         
                           University of California v. Eli Lilly & Co., 119 F.3d 1559, 43                                            
                           USPQ2d 1398 (Fed. Cir. 1997)] disclosure rule does not require a                                          
                           particular form of disclosure because one of skill could determine                                        
                           from the specification that the inventor possessed the invention at                                       
                           the time of filing.                                                                                       
                           On this record, the examiner bases his rejection on an incorrect                                          
                   interpretation of the claimed invention.  Contrary to the examiner’s assertion                                    
                   (Answer, page 4), claims 3 and 16 do not require the inhibition of CAT2                                           
                   translation.  Instead, claim 16 is drawn to an antisense oligonucleotide directed                                 
                   against CAT2 mRNA, and claim 3 is drawn to a composition comprising an                                            
                   antisense oligonucleotide directed against CAT2 mRNA in a physiologically                                         
                   acceptable carrier.  We note that while a number of appellant’s claims are                                        
                   directed at methods of using an antisense CAT2 oligonucleotide, none of these                                     
                   claims are included in this rejection.                                                                            








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