Ex Parte Murugesan et al - Page 6


                Appeal No. 2002-0522                                                  Page 6                  
                Application No. 09/552,543                                                                    

                characteristics of a fluid are what make the segmentizing medium work in this                 
                invention.”  480 F.2d at 1383, 178 USPQ at 284.                                               
                      The Smythe court made clear that its conclusion was based on the                        
                specific facts of that case.  See id.  (“Each case must be decided on its own                 
                facts.”).  Smythe did not hold that disclosure of a species always provides a                 
                description of an encompassing genus.  In fact, the Smythe court pointedly noted              
                that the facts of that case were distinguished from                                           
                      other cases, particularly but not necessarily, chemical cases, where                    
                      there is unpredictability in performance of certain species or                          
                      subcombinations other than those specifically enumerated, [where]                       
                      one skilled in the art may be found not to have been placed in                          
                      possession of a genus or combination claimed at a later date in the                     
                      prosecution of a patent application.                                                    
                Id. at 1383, 178 USPQ at 284-285.  This case falls squarely into the category of              
                cases that the Smythe court distinguished.  See, e.g., In re Fisher, 427 F.2d 833,            
                839, 166 USPQ 18, 24 (CCPA 1970) (“In cases involving unpredictable factors,                  
                such as most chemical reactions and physiological activity, the scope of                      
                enablement obviously varies inversely with the degree of unpredictability of the              
                factors involved.”).                                                                          
                      In fact, the Federal Circuit recently cited Smythe, along with Fiers v.                 
                Revel, 984 F.2d 1164, 25 USPQ2d 1601 (Fed. Cir. 1993), as authority for the                   
                proposition that a “written description of a chemical genus, like a description of a          
                chemical species, ‘requires a precise definition, such as by structure, formula,              
                [or] chemical name,’ of the claimed subject matter sufficient to distinguish it from          
                other materials.”  University of California v. Eli Lilly and Co., 119 F.3d 1559,              






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