Ex Parte HAIK - Page 9


                    Appeal No.  2002-1874                                                                     Page 9                        
                    Application No.  09/079,329                                                                                             

                    L-isomer renders the use of the D-isomer obvious.  But “conclusory statements”                                          
                    as to teaching, suggestion or motivation to arrive at the claimed invention “do not                                     
                    adequately address the issue [of obviousness].”  In re Lee, 277 F.3d 1338, 1343-                                        
                    44, 61 USPQ2d 1430, 1433-34 (Fed. Cir. 2002).                                                                           
                            Because the examiner has failed to set forth a prima facie case of                                              
                    obviousness, the rejection is reversed.                                                                                 
                            Claims 47-49, 54-56 and 237-244 stand rejected under 35 U.S.C.                                                  
                    § 103(a) as being obvious over the combination of Khaidar and Lo.                                                       
                            According to the rejection, Khaidar teaches that reactive species such as                                       
                    methylglyoxal, which are found in the blood, mediate the cross-linking of                                               
                    physiological proteins, and that arginine can reduce that cross-linking, “it would                                      
                    have been obvious to treat blood to remove this by-products and to use arginine                                         
                    for their removal.  As dialysis is a routine procedure for removal of unnecessary                                       
                    contaminations from blood, it would be obvious to remove methylglyoxal or other                                         
                    carbonyls using dialysis system.”  Examiner’s Answer, page 8,                                                           
                            Appellant argues that the combination of Khaidar and Lo does not render                                         
                    obvious the claimed invention.  Appeal Brief, page 5.  We agree.                                                        
                            This rejection suffers the same deficiencies as the prior obviousness                                           
                    rejection, and for the reasons set forth with respect to that rejection, the rejection                                  
                    of claims 47-49, 54-56 and 237-244 over the combination of Khaidar and Lo is                                            
                    also reversed.                                                                                                          
                                                              REVERSED                                                                      







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