Ex Parte Zhang et al - Page 8



           Appeal No. 2003-0061                                                                     
           Application No. 09/611,109                                                               

           and wherein one or more methylene groups are optionally replaced                         
           by O, NH, S(O), S(O)  or S, wherein said methylene groups are2                                                                
           further optionally independently substituted with 1-2 oxo groups                         
           and one or more C  branched or unbranched alkyl optionally1-4                                                                  
           substituted by one or more halogen atoms;                                                
                   Q is selected from the group consisting of:                                      

           a) phenyl, naphthyl, pyridine, pyrimidine, pyridazine,                                   
                imidazole, benzimidazole, furan, thiophene, pyran,                                  
                naphthyridine, oxazo[4,5-b] pyridine and imidazo[4,5-b]                             
                pyridine, which are optionally substituted with one to three                        
                groups selected from the group consisting of halogen, C1-6                          
                alkyl, C  alkoxy, hydroxy, mono- or di-(C alkyl)amino, C1-6                                   1-3                1-6             
                alkyl-S(O)  and phenylamino wherein the phenyl ring ism                                                                        
                optionally substituted with one to two groups selected from                         
                the group consisting of halogen, C  alkyl and C  alkoxy;1-6           1-6                           
           b) tetrahydropyran, tetrahydrofuran, 1,3-dioxolanone, 1,3-                               
                dioxanone, 1,4-dioxane, morpholine, thiomorpholine,                                 











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