Ex Parte LEE - Page 2


                  Appeal No. 2003-0528                                                            Page 2                   
                  Application No. 09/314,841                                                                               
                         The references relied upon by the examiner are:                                                   
                  Schwinn et al. (Schwinn)                   4,297,344             Oct. 27, 1981                           
                  Butler et al. (Butler)                    5,358,853             Oct. 25, 1994                           
                  Prestrelski et al. (Prestrelski)           5,580,856             Dec.  3, 1996                           
                  Hawkins et al. (Hawkins)                   5,625,036             Apr. 29, 1997                           
                  Hora et al. (Hora)                        5,730,969             Mar. 24, 1998                           
                  Brown                                    5,314,695             May 24, 1994                            
                  Brucato, et al. (Brucato)                  WO 98/48283           Oct. 29, 1998                           
                  Mimms et al. (Mimms), “Phospholipid Vesicle Formation and Transmembrane                                  
                  Protein Incorporation Using Octyl Glucoside,” Biochemistry, Vol. 20, pp. 833-840                         
                  (1981)                                                                                                   
                                              GROUNDS OF REJECTION                                                         
                         Claims 1, 2, 5, 7-11, 16-19, 21, 39, 43-45, 48-51, 53 and 54 stand                                
                  rejected under 35 U.S.C. § 103 as being unpatentable over Brucato in view of                             
                  Butler and Schwinn.                                                                                      
                         Claims 22, 29, 31, 32, 34, 35, 37 and 38 stand rejected under 35 U.S.C.                           
                  § 103 as being unpatentable over Brown in view of Brucato, Butler and Schwinn.                           
                         Claims 12, 13, 41 and 42 stand rejected under 35 U.S.C. § 103 as being                            
                  unpatentable over Brucato in view of Butler, Schwinn and Hawkins.                                        
                         Claims 24 and 25 stand rejected under 35 U.S.C. § 103 as being                                    
                  unpatentable over Brown in view of Brucato, Butler, Schwinn and Hawkins.                                 
                         Claims 4, 20, 26, 33, 36 and 52 stand rejected under 35 U.S.C. § 103 as                           
                  being unpatentable over Brucato in view of Butler, Schwinn and Prestrelski with                          
                  or without Brown.                                                                                        
                         Claims 14, 15, 27, 28, 46 and 47 stand rejected under 35 U.S.C. § 103 as                          
                  being unpatentable over Brucato in view of Butler, Schwinn and Hora with or                              
                  without Brown.                                                                                           







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