Ex Parte MANDEVILLE et al - Page 2


                 Appeal No. 2003-0564                                                        Page 2                   
                 Application No. 08/964,498                                                                           

                        9.     The method of Claim 1 wherein the polymer comprises a repeat                           
                        unit of the general formula                                                                   









                 wherein R1 and R2 are each, independently, is hydrogen, a substituted or                             
                 unsubstituted, normal, branched or cyclic alkyl group, or a substituted or                           
                 unsubstituted aryl group; or R1, R2 and the nitrogen atom together form a cyclic                     
                 system; and X is a pharmaceutically acceptable anion.                                                

                        The examiner relies on the following references:                                              
                        Howes                            2,090,605            Dec. 12, 1980                          
                        Holmes-Farley               WO 95/05184                Feb. 23, 1995                          
                        Claims 9-18 stand rejected under 35 U.S.C. § 103 as obvious in view of                        
                 Howes and Holmes-Farley.1                                                                            
                        We reverse.                                                                                   
                                                    Background                                                        
                        Elevated phosphate levels, or hyperphosphatemia, “frequently                                  
                 accompanies diseases associated with inadequate renal function,                                      
                 hypoparathyroidism, and certain other medical conditions.”  Specification, page                      
                 1.  The condition can cause “aberrant calcification in joints, lungs, and eyes.”  Id.                
                                                                                                                      
                 1 The rejection based on Howes and Holmes-Farley is the only rejection applied to the claims,        
                 despite the examiner’s statement that he “could just as well make the rejection combining newly      
                 submitted Patent Document EPA 793960.”  Paper No. 19, mailed Nov. 7, 2000, page 2.  The ‘960         
                 reference was not cited as a basis for the rejection, nor did the examiner provide any explanation   
                 whatsoever of how it might form a basis for rejecting the claims.  To the extent that the examiner   





Page:  Previous  1  2  3  4  5  6  7  8  Next 

Last modified: November 3, 2007